Initial Diagnosis | Tumour marker Used | Diagnosis after marker study | Final Diagnosis |
Inconclusive | SMA And Vimentin +ve | Leiomyosarcoma | Leiomyosarcoma |
Suggestive of spindle cell neoplasm? Neurilemmoma | +ve for EMA & Focal CK -ve for Desmin, S-100 & CD-99 | Synovial cell sarcoma | Synovial cell sarcoma |
Benign epithelial Neoplasm | +ve for CK, Chromogranin, Synaptophysin & bcl-2 | Neuroendocrine tumours | Neuroendocrine tumours |
Monomorphic salivary adenoma | +ve for CK, Chromogranin, Synaptophysin & bcl-2 | Neuroendocrine tumours | Neuroendocrine tumours |
Spindle cell Neoplasm | +ve for SMA & S-100 -ve for CK | Benign Myoepithelioma of deep lobe parotid | Benign Myoepithelioma of deep lobe parotid |